This is the first report of a cryptogenic stroke patient in whom PPG-based mHealth (FibriCheck) was able to detect the occurrence and burden of paroxysmal atrial fibrillation (AF) episodes with similar precision as an insertable cardiac monitor (ICM). ICMs are the most performant rhythm monitoring devices according to studies device but they are expensive, invasive, and currently underutilized. This case demonstrates the feasibility and accuracy of implementing FibriCheck monitoring as a low-cost and non-invasive tool.
These results were published in Front. Cardiovasc. Med. by Femke Wouter et al (2022).
The full case report can be accessed here.
|Medication||Chlortalidone 50 mg
Quinapril 20 mg
Atenolol 25 mg
|Lifestyle||Sedentary lifestyle and former smoker|
|Admission||The patient woke up with aphasia and a headache. He presented himself to the emergency department the next day with normal vital parameters and word-finding difficulties|
No electrolyte or metabolic disturbances
LDL cholesterol level: 79 mg/dl
Total cholesterol: 145 mg/dl
|Heart rhythm monitoring||
67h ECG monitoring stroke unit
Within the scope of this study, the cryptogenic stroke patient was instructed to perform two one-minute spot-checks using the FibriCheck application each day, and additional spot-checks could be performed in case of symptoms during a period of 6 months.
Comparison between ICM and FibriCheck results
Before the ablation procedure, five AF episodes were detected on both the ICM and FibriCheck. The AF episodes were concurrently detected by an ICM and FibriCheck with an artificial intelligence algorithm to detect AF. The application detected all AF episodes identified by the ICM. Moreover, there were no false-positive FibriCheck recordings. Only three AF recordings (19%) were symptomatic (i.e., palpations and dizziness); two of these were recorded within the same hour.
Timeline of continuous and spot-check measurements performed by ICM and FibriCheck. A seven-day ECG Holter was used in the first month. At the end of the second month, the ICM was inserted, and the use of FibriCheck was initiated. Green bars indicate a sinus rhythm, red bars indicate an AF episode, dark red bars indicate a symptomatic AF episode as reported in the FibriCheck app, blue bars indicate insufficient data quality, and the black bar indicates the ablation.
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